Aloe vera is one of the oldest mentioned plants in the medicinal literature. Its abundance of health benefits is one primary reason why it is being used since ancient ages. Apart for its use to decor home gardens, it can be used to relieve the sunburns, wart removal and various skin ailments.
Aloe vera leaves contain the translucent, mucilaginous gel which said to made up of 99% water and 1% of other bioactive chemicals like carbohydrates, proteins (knowns as lectins), minerals, sugar, salicylic acid, and saponin. 
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Can aloe vera cure HPV?
Though there are no significant studies that involve assessment of aloe vera gel on the HPV, some recent studies show that aloe vera gel can fight against the viruses and other microbes.
Simply put, aloe vera gel may work to remove the wart and it can even be applied to genital warts as usually, it does not cause skin irritation.
How does it work?
Aloe vera gel is extracted from the leaves of aloe vera. One can apply it directly to the skin or can buy available gel formulations in the market.
It works by moisturizing wart and surrounding skin and exhibiting its medicinal action. Aloe vera gel found to contain salicylic acid, lectins, and minerals which are believed to be responsible for the wart removal.
Salicylic acid is a well know wart remover and is FDA approved ingredients for various topical wart removal gel and creams. Lectins in the aloe vera gel found to have tumor prevention effect when given in prophylactic dose in the mice. 
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How to use aloe vera gel for wart removal?
To use aloe vera gel to get rid of warts follow the given instruction:
- Cut a fresh aloe vera leaf and clean it thoroughly.
- Remove the pulp in a dish.
- Soak the wart in lukewarm water for 15 to minutes.
- Paint the wart with aloe vera gel and leave it for an hour or two, then wash it off.
- Repeat the procedure daily for 15 to 20 days and see the results.
- If things didn’t work, consult your doctor. [/thrive_text_block]
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Risk factors to consider
Though the topical application of an Aloe vera gel is considered safe, in some cases it may cause slight burning, hives or rash. If the burning continues or rashes increases then consult your doctor.
Aloe vera products are not regulated by the FDA, so while purchasing any product you should pay attention to the authenticity of the company, whether the product has any external laboratories quality certificate, etc.
Also, aloe vera should never be applied over the open wound or burns as may lower the healing ability of skin tissues.
Before using any topical application of aloe vera gel over the face or genital warts, make a habit to perform a small patch test. Take a small amount of aloe vera gel over applicator and apply it over the skin around the elbow and wait for 15 to 20 minutes.
If you get any reactions, do not use the gel and if you tolerate the application well then you can apply it over warts or for other skin problems.
Though people practice it, taking aloe vera orally is not recommended. It may cause stomach discomfort, abdominal pain and have laxative action on the gastrointestinal tract.
[thrive_text_block color=”light” ] Bottom Line: Aloe vera gel can moisturize your skin, reduce burning and may help to treat the wart to a certain extent. As it rarely causes skin burning, it can be applied over face and genital warts.
But considering the amount of salicylic acid and lectins that it contains, we believe that it will hardly show the significant cure for warts. [/thrive_text_block]
 Phytochemical constituents of Aloe Vera and their multifunctional properties. Author – Sanjit Kumar Kar and Tushar Kanti Bera DOI: 10.13040/IJPSR.0975-8232.9(4).1416-23
 Rezazadeh, F., Moshaverinia, M., Motamedifar, M., & Alyaseri, M. (2016). Assessment of Anti HSV-1 Activity of Aloe Vera Gel Extract: an In Vitro Study. Journal of dentistry (Shiraz, Iran), 17(1), 49–54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771053/
 Hussain, A., Sharma, C., Khan, S., Shah, K., & Haque, S. (2015). Aloe vera Inhibits Proliferation of Human Breast and Cervical Cancer Cells and Acts Synergistically with Cisplatin. Asian Pacific Journal of Cancer Prevention, 16(7), 2939–2946. DOI: 10.7314/apjcp.2015.16.7.2939
 Tumour preventive effect of Aloe vera leaf pulp lectin (Aloctin I) on Ehrlich ascites tumours in mice. DOi: 10.1002/ptr.2215